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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd9673f95d4184ea733949e39395f616c67901edbac95d27503ff4b19ef901d21' 
  AND token = 'sVSrlO4O3NP78nvJF4rNjl4wSI10OS8y67ScPsIIhWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}