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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '49c61b96539bc844642ebf0f9452af8ae4867461c659d98b100e1b8101b4c043' 
  AND token = 'WxBSy5fnpTEBVaa3+JvHa7dgqdaXcZpPbLvAWAsC36M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}