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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'de0e0f1c0b6048cf15fefc1c62c1b4602982106a89425111c5c90e4db383285c' 
  AND token = 'xw+FVFhiOLj0IQybClATfDcuN+jP05UwLwhcHcr9n0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}