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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a43b23a3dc52d0f88239b6ef1541395450c764fb4da44654c5e894e92f4a0bde' 
  AND token = 'vEN6J7HjB7finWzmccF4WcOyegrFrKy7tbE12ia9Sfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}