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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f0a857cd23ba571528571022d4b9d259d3f647fe19660ebab8afeded79cb66a5' 
  AND token = 'dE9xo8bJF05A9uHThtD987D62FhYRastHzw6m8xW5dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}