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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '70e9ed1754b6e397e5890668fd3979099be8619d4c431a49749303994b1c8f46' 
  AND token = 's3sjhBTmq/tL9/uYJixHnL7NAhDDRBNm2JxFmuT2eFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}