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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '593c1b920abddcb5ab827c2a536ba0c3ac019fbe5e5560d427dfd724d800bbf3' 
  AND token = 'TdmUPHyTwyCsfMC43zICzezljmg63iEleolBOYKhQro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}