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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '65d95660c124228e47c9cda2918a72366ca4ee117c76e33d880a35fd1c1da87b' 
  AND token = 'OxLlkA2O++U6AIQFct9Ex8hI9KDFHEBdY5wDB9f0uDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}