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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a5e9c356b32892a599729d51a67fe8329a0260cbeb59239cc972429848a6f2af' 
  AND token = '5t1h/awBi2vReWbDAvPJH619VdffEIM9gdCahntXq0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}