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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b011f514741a43ca8754a9aee46d51b98388ef68c3487ed1d7b503569a56a8f1' 
  AND token = 'pAjTbViGkPPfP+uQQR7iLwueFH4j8fgBAO9ORJdUQDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}