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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0f618f1967e09a81c18f5af82459bea080920cf49d6324a8d5c54ef80c5c3ac6' 
  AND token = 'juhde8r390+i8eEqtOZH7cwda8uLDYutqMTBBWMQ34I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}