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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4e657b7c986cde456f1ab873fcefe5259d9d960dfb48f8c39f898b95b9738319' 
  AND token = 'KkDzri8evhUIkZ9/xCz3OspEQcescyCyZLJ5WiPvfcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}