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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e0e06ccb708a9551bfeb256db1c9b2f7ad50891d656dee75b505171a6202c728' 
  AND token = 'y1NDoeqwUm2/9k0DnGyem+u2OVsUF2g4/Vdja7wq260=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}