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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '47df79371247a8a838fc898e5bb8b6660e241c279fe5ca80010d49517ac5f3a0' 
  AND token = 'WUkTSEtSHRlTfA1hfMwDrh8X1cfYTAlW7afNsFdYOh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}