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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f8ed3a573fe5a357d76c2e64ab177d32474f54defb0ed7cafd810bc72427cd78' 
  AND token = '3cstWqI3Ztsl5yGOkyN0qYrfzOURer27sgMzMF83jhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}