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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6c581493b411f48d7041fb2b745c7bb6f683d54ef84f497643b3d01bdc4dbc0d' 
  AND token = 'GMScmVjjmoXk3kcjrZE0lzrzT6lLX89XnwbYF6DRHG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}