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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f4ee706f3da261304c0126170be2621c6fedc6fa47505c58d15565482b80b19c' 
  AND token = 'RXcr1mPTM/ZrOwErueFEw4j3eNa1jz8JV0abZLRN/hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}