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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0043ea157916bc122b4410abce08556cda8649dd3ba9a570fc3b380ce2bc4e98' 
  AND token = '7OVUqBjNBFjBSE2lR6Rq/P3b/ctRbC0USUyAA81/Au4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}