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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2d0e3f98b7dcacb4a6071b7ad8328d281ef793fc614ca4df19cd6efd3a549045' 
  AND token = 'ILX9209x2prOuMY8qybwc+SmxgfMxuu0P7UlSjpcib8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}