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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '544a43e35ed411e110159a8d1bcfe8b6ad18b1c3b575a85bed727e1b176dec12' 
  AND token = '3I6Sm7rnAbankS++mpBCq6XDYCg2fW+60FcgNc+8v7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}