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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ef1e5344a67d6011a076cca99e9b14529d654b867ba9ca345c115ff021591e88' 
  AND token = 'Bc+nBCDccmKZ/BfSVm6pratpm4KjtZZAI+QLiuki9KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}