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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a34ad6f998eab3ae4f45f00e4023a0c97bb325b568450c99a329b986f1c0564c' 
  AND token = 'T7KPyPaRZM1AEA1tz9hhnB7kuR7KnOWjc1P7hK5tWI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}