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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '41327b261efd31fe9d6c470d6b1f1950ba84a518f90d1614e650f599b29376be' 
  AND token = 'dk1ZPuyiYiMiHRXQ0SPKlJIaGs10dxoKcAfM8v2pw38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}