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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '425cacb10620c0edba2dd8655ddf1d984b08e8a7075ff9930bfa15e7909ab514' 
  AND token = 'yhKqBDjf+Nsi8xv69s9/up8xkzQDQ6N+F2Nvf0/b5Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}