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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '343538926488f8fd98e88119e1981405cfdbb4d4834a0f5f279a25f981a2abdd' 
  AND token = 'W76NfrQYpRjSwd/lmdR79BH4utz/QgR7jKVuBieWM18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}