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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '41d1d74e25e1383d09c66628922197b03545b10208b3de770191d1f2c8faada5' 
  AND token = 'opxRUSy/TxAHcEZT/o4pmHHdmdSrUB6RPfgqpX7MzaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}