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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8ef9c2a2cc0e806629cae3653278a64e378bc73c02d92887799c218d6a80fea9' 
  AND token = 'jr/rtgOl7x9+FMMLlqpmtep65B+cC9+TPAhsffQKpSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}