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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6646277456b0ee7e5604322b65f981edd390bbd32691338037d6f8b678c28627' 
  AND token = 'Zj+0rX/Scm3EkUyzNse1w3o2m64k89h1WWTqsSH2EPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}