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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bfee7612052409e7857b58528ddf5952a557cb5e880779a886411a7c50f2b372' 
  AND token = 'xNyA2Y2rEc6USaSl688BSwtvA5Dpiyc6KQ4EbjyrylQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}