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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'dbdde2a3c6da425ae02a870cdfa0944cd61ee5f66f422575e113146042a391b5' 
  AND token = 'xHo5mInO1df+iGbWfvaLQjqY/ebS7qvh44EmbMwPxaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}