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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ee10ff454a7f642de9bec8174772c2d2ecf2750e056516c6df01530fe6549364' 
  AND token = 'GQ0D8kcZR1A3bJxToOkVmKedcpsM5NarkAJYPjDa4cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}