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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2e6a9c52bed13d531964c3aee9a0bec2729d95a833557b27359ae2e596e22055' 
  AND token = 'PohE+ZxWfscVlsmMhLZL04HRqr7FgHW1ko5Z62HVf3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}