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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '77ef75363949a90b7b71daf58c442f1f877b805f764c04b1bbb4244fef3815b6' 
  AND token = '6sWshAEy0D1nEXFqALLOpNTOtHkHbmrK2v2MjQVMVH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}