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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bffeb41d4e14a1d2cb4a391b0b7a014be25d89a031a41e88020200beec26e548' 
  AND token = '6rSkK1uXCDNjaxa7X17NejizCCHDrqD2ElTX9IjqdcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}