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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bc6d8f376b8c00c8412d37c79842991018b832f8048a346df4fed7f10d4420cc' 
  AND token = 'y4RKDv6FHSTf2W43gCTE4xwY4rRQRSbvOCVRvqBNg4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}