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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f80affb6341cdc438fcd5b0bdbe9fb10aec901f95e74d073f3d9aa42959a1d07' 
  AND token = 'A1uW5ssVOn+dwzK8j35TsiW00lQmzmxsSufY5r5aZ4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}