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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f3992de1c106a933c137067d3e8b47352845e4fa33f6b6840c21074fccb02f49' 
  AND token = 'JA2ICl2AFQlw4twmQXnlKFAD2lKDOnkXzubN8HajFAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}