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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9eda4093ce3b91aa30da7c4a25ff106c840243ba813f797032e364da89e991a4' 
  AND token = 'APVdx2hYuiTMxPSfjiKm2tk9dKMfthG4MWiQc4v0Qws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}