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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '553f80809ed91d46d1d68176038e4cfeefcae89501e318f7aa7c90c57708a3a6' 
  AND token = '74LrnOatvBFxlMAWSUbGb5PIiD8y/d2gGTG03tIOqRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}