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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '08d1beffa4c13dcf2a219e28c32fc8382728fa482cc12c2582a61d392b3f4563' 
  AND token = 'VBdTqEzm0bx22c6sQsth2puSmDnc+hrGZ6xRmYVMp6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}