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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a5e02f72666024641ce2f32e1b5d09d98c81dedb748645d6e72d9b53d5d3bc0d' 
  AND token = 'GZrPIyP8ymxYensDvu4F+Ax3lTn5YcRqfmCPEbP9gno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}