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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2d18925ec22a22f622776814d3bb750a89a16b5e1ea651d2978ae2d78b8cbd79' 
  AND token = 'kpV6MCNoMJi0CKEl/LqVIkyyt830TzIb9UNyPs6/398=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}