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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c427d83b8ca5943f65595bc9bc05f90a008294fca9ef98edc8e1884a91f50034' 
  AND token = '7t71PmPJsiuRgzPFF4DBVRCCas32NDgPumWDGSZNfAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}