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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e458e622e811e8f55e95ba7ac2b66ddd470ffe523974117213e362636fa49813' 
  AND token = '2jgwpfq8hsj7+1w9JOA/aq41K7XbVn6IPIw6+ts+csk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}