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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ce224ac739266c2282e0c034ef13f7bba4078f180ac09f8da60c904c25f151e2' 
  AND token = 'jiYy94T+DOW891u3hS2yntmehv3rlFnQYoi1/j5z+bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}