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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b2d157495e8459835be491aed02e5b572221824b92cabb441fc42cf15b0fc9af' 
  AND token = 'pu0fqBVKjg7ZoW3A4DVW9xtHcgoe3+iN7WDH9Et57dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}