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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6e8d31fce515886180d9279beea71d5811abfa332a0820927c859305873290a1' 
  AND token = '6I9VF0DSlec/2uCsto1LgBoZpNKQE97hCwuscrQXqts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}