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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e0192686eef246c7b269008062ca53a41a4126acf877a557614491e18d0a3022' 
  AND token = 'YUXs48qv4k0COymy8Xap8y8zCelOqWU7y2tAtrv5OAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}