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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '14a3a226f079915d4a50200b9a1bf1d5ce4ea0b95896e53825397da02d14e297' 
  AND token = 'J4baiRY3+8sBAm5y4YjFDMleb1ipTt70TZ8xBef7Wvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}