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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '80de894ae89101331b85ddcd24284f4b03ba5bea8742f542608a8d268ce3d962' 
  AND token = 'Co2TNBwfWj5SvtuOTF9qOrECEjisHrTQlkao9ZOCO+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}